{"id":92888,"date":"2020-08-05T21:02:29","date_gmt":"2020-08-05T21:02:29","guid":{"rendered":"https:\/\/raed.academy\/?p=92888"},"modified":"2020-08-06T10:42:18","modified_gmt":"2020-08-06T10:42:18","slug":"del-laboratori-a-la-farmacia-desenvolupament-dels-farmacs","status":"publish","type":"post","link":"https:\/\/raed.academy\/ca\/del-laboratori-a-la-farmacia-desenvolupament-dels-farmacs\/","title":{"rendered":"Del laboratori a la farm\u00e0cia"},"content":{"rendered":"

Francisco L\u00f3pez Mu\u00f1oz<\/strong><\/em><\/a>
\nProfessor de Farmacologia i vicerector de Recerca i Ci\u00e8ncia i director de l’Escola Internacional de Doctorat de la Universitat Camilo Jos\u00e9 Cela. <\/em>Acad\u00e8mic de n\u00famero de la Reial Acad\u00e8mia Europea de Doctors-Barcelona 1914 (RAED)<\/em><\/p>\n

Confer\u00e8ncia difosa per streaming i publicada pel canal especialitzat “DiarioSalud”
\n<\/em><\/p>\n

Francisco L\u00f3pez Mu\u00f1oz<\/strong>, professor de Farmacologia de la Universitat Camilo Jos\u00e9 Cela<\/strong> i acad\u00e8mic de n\u00famero de la Reial Acad\u00e8mia Europea de Doctors-Barcelona 1914<\/strong> (RAED), explica d’una manera did\u00e0ctica el proc\u00e9s de recerca i de desenvolupament dels f\u00e0rmacs en una confer\u00e8ncia organitzada per l’Acad\u00e8mia Dominicana de Medicina<\/strong> i el canal especialitzat “DiarioSalud”<\/strong> el passat 30 de juliol que es va transmetre per streaming i que est\u00e0 disponible al web i el canal de YouTube de “DiarioSalud”.<\/p>\n

L’acad\u00e8mic va iniciar la seva exposici\u00f3 explicant que qualsevol recerca sobre un nou f\u00e0rmac s’inicia amb un complex examen de m\u00e9s de 10.000 compostos qu\u00edmics en la seva fase inicial. D’aqu\u00ed, per eliminaci\u00f3, els investigadors redueixen aquesta xifra fins als 250 compostos al denominat per\u00edode precl\u00ednic, que pot durar fins a sis anys, i que inclou ja l’experimentaci\u00f3 amb animals. A partir d’aqu\u00ed la recerca ha d’arribar als cinc o sis compostos als quals es limiten els assajos cl\u00ednics sobre persones, primer amb ciutadans sans i despr\u00e9s amb malalts. Un nou proc\u00e9s que s’allarga fins als set anys. Finalment arriba l’aval de les autoritats sanit\u00e0ries, que solen trigar una mitjana d’un any a un any i mig a avaluar un nou f\u00e0rmac i aprovar-lo per al seu \u00fas m\u00e8dic. En definitiva, el proc\u00e9s sencer acostuma a durar de 10 a 15 anys, tenint en compte a m\u00e9s que es donen nombrosos fracassos al llarg del proc\u00e9s.<\/p>\n

\"Francisco

Dr. Francisco L\u00f3pez<\/p><\/div>\n

L\u00f3pez Mu\u00f1oz<\/strong> va explicar que la clau de l’\u00e8xit en el desenvolupament de qualsevol nou medicament rau en la identificaci\u00f3 de dianes biol\u00f2giques. Per a aix\u00f2 cal con\u00e8ixer a fons la malaltia sobre la qual es pret\u00e9n actuar, con\u00e8ixer l’agent infecci\u00f3s o les mancances biol\u00f2giques que la produeixen i donar amb els transportadors adequats per conduir aquestes subst\u00e0ncies farmacol\u00f2giques que s’hagin determinat efectives al lloc adequat perqu\u00e8 interaccionin amb l’organisme. Aix\u00ed mateix, qualsevol desenvolupament farmacol\u00f2gic ha de tenir en compte la toxicitat i efectes secundaris que pot desenvolupar un nou f\u00e0rmac.<\/p>\n

En la seva xerrada, l’acad\u00e8mic va destacar el factor de la casualitat que s’ha donat al llarg de la hist\u00f2ria en el descobriment de nous f\u00e0rmacs, amb la penicil\u00b7lina o la vacuna de la verola com a exemples paradigm\u00e0tics. Destacant que no \u00e9s nom\u00e9s l’atzar, sin\u00f3 la sagacitat dels investigadors per determinar que en un fet casual pot trobar-se una soluci\u00f3 efectiva i investigar-ne. Aquest \u00e9s un camp sobre el qual L\u00f3pez Mu\u00f1oz incideix en els seus \u00faltims estudis.<\/p>\n

 <\/p>\n

Veieu la confer\u00e8ncia<\/a><\/h3>\n","protected":false},"excerpt":{"rendered":"

Francisco L\u00f3pez Mu\u00f1oz, sobre el proc\u00e9s d’investigaci\u00f3 i de desenvolupament dels f\u00e0rmacs<\/p>\n","protected":false},"author":12,"featured_media":92846,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[213],"tags":[],"class_list":["post-92888","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina-i-cirurgia","et-has-post-format-content","et_post_format-et-post-format-standard"],"yoast_head":"\nDel laboratori a la farm\u00e0cia - Reial Acad\u00e8mia Europea de Doctors<\/title>\n<meta name=\"description\" content=\"Francisco L\u00f3pez Mu\u00f1oz, sobre el proc\u00e9s d'investigaci\u00f3 i de desenvolupament dels f\u00e0rmacs\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/raed.academy\/ca\/del-laboratori-a-la-farmacia-desenvolupament-dels-farmacs\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Del laboratori a la farm\u00e0cia - 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