{"id":161560,"date":"2025-04-09T10:52:35","date_gmt":"2025-04-09T10:52:35","guid":{"rendered":"https:\/\/raed.academy\/?p=161560"},"modified":"2025-04-09T10:52:35","modified_gmt":"2025-04-09T10:52:35","slug":"la-melatonina-i-la-guerra-quimica","status":"publish","type":"post","link":"https:\/\/raed.academy\/ca\/la-melatonina-i-la-guerra-quimica\/","title":{"rendered":"La melatonina i la guerra qu\u00edmica"},"content":{"rendered":"
\"Dr.

Dr. Francisco L\u00f3pez Mu\u00f1oz<\/p><\/div>\n

Francisco L\u00f3pez Mu\u00f1oz<\/strong><\/em><\/a>, catedr\u00e0tic de Farmacologia i vicerector de Recerca, Ci\u00e8ncia i Doctorat de la Universitat Camilo Jos\u00e9 Cela<\/strong>, membre fundador del Comit\u00e8 d’Observaci\u00f3<\/strong> de l’Observatori de Drets Humans d’Espanya<\/strong>, acad\u00e8mic corresponent de la Reial Acad\u00e8mia de Medicina del Pa\u00eds Basc<\/strong> i acad\u00e8mic numerari de la Reial Acad\u00e8mia Europea de Doctors<\/strong> (RAED), aborda les caracter\u00edstiques menys conegudes d’un producte d’\u00fas habitual que a Europa no arriba a considerar-se un medicament a l’article “La melatonina y la guerra qu\u00edmica: por qu\u00e9 la inversi\u00f3n en defensa tambi\u00e9n debe cubrir la protecci\u00f3n m\u00e9dica”<\/strong>, que es va publicar al portal especialitzat The Conversation<\/strong> el passat 18 de mar\u00e7 i, despr\u00e9s, en diversos mitjans de comunicaci\u00f3 espanyols. L\u00f3pez Mu\u00f1oz firma aquest article al costat d’Alejandro Romero Mart\u00ednez<\/strong> i Eva Ramos Alonso<\/strong>, professors de Toxicologia de la Facultat de Veterin\u00e0ria de la Universitat Complutense de Madrid<\/strong>.<\/p>\n

Els tres experts, que ja van incidir en les caracter\u00edstiques de la melatonina a l\u2019article “Los tres peligros de la melatonina: un f\u00e1rmaco vendido como suplemento alimenticio en Espa\u00f1a”<\/strong><\/a>, que van publicar el juliol passat al diari “El Espa\u00f1ol”<\/strong>, s’aturen ara a analitzar el seu potencial terap\u00e8utic davant agents qu\u00edmics que poden utilitzar-se com a armes, ja que la melatonina pot ser efectiva davant una \u00e0mplia varietat de patologies com ara diferents tipus de c\u00e0ncer, alteracions gastrointestinals, malalties cardiovasculars, processos neurodegeneratius i patologies autoimmunes i infeccioses. Aquest potencial terap\u00e8utic tan vers\u00e0til es deu a la seva capacitat per regular m\u00faltiples processos bioqu\u00edmics en l’organisme.<\/p>\n

“La melatonina, coneguda m\u00e9s habitualment per regular el cicle son-vig\u00edlia, \u00e9s un potent antioxidant amb baixa toxicitat i amb gran facilitat per travessar les barreres biol\u00f2giques, la qual cosa la posiciona com una possible opci\u00f3 terap\u00e8utica davant aquestes armes qu\u00edmiques. A trav\u00e9s de la transfer\u00e8ncia d’\u00e0toms d’hidrogen i formaci\u00f3 de radicals, la melatonina pot neutralitzar esp\u00e8cies reactives d’oxigen i nitrogen. A m\u00e9s de neutralitzar els danys per oxidaci\u00f3 de les estructures cel\u00b7lulars, la capacitat per modular la resposta inmuno-inflamat\u00f2ria de la melatonina podria ser crucial per mitigar les greus lesions en mucoses i estructures internes tissulars provocades per l’exposici\u00f3 a aquests agents qu\u00edmics”, expliquen.<\/p>\n

L\u00f3pez Mu\u00f1oz, Romero Mart\u00ednez i Ramos Alonso consideren que at\u00e8s el seu origen natural i excel\u00b7lent tolerabilitat, nombroses evid\u00e8ncies indiquen que l’administraci\u00f3 de la melatonina com a adjuvant en combinaci\u00f3 amb altres f\u00e0rmacs podria no nom\u00e9s protegir davant la toxicitat dels agents qu\u00edmics de guerra, sin\u00f3 tamb\u00e9 millorar l’estat de salut dels pacients en determinades condicions i, amb aix\u00f2, reduir els efectes secundaris de la ter\u00e0pia qu\u00edmica habitual. “En vista d’aquest enorme potencial, i malgrat el seu ampli \u00fas com a reguladora del son, la melatonina podria tenir aplicacions importants com a contramesura davant armes qu\u00edmiques i diverses patologies. Per aix\u00f2, \u00e9s fonamental impulsar estudis cl\u00ednics multic\u00e8ntrics estandarditzats per avaluar la seva efic\u00e0cia i seguretat a llarg termini, especialment a les dosis farmacol\u00f2giques elevades que molt possiblement requeriria el seu \u00fas cl\u00ednic”, afegeixen.<\/p>\n

\"\"Per aix\u00f2 els signants de l’article de The Conversation advoquen per una inversi\u00f3 en defensa que tingui tamb\u00e9 molt en compte la recerca que permeti millorar la capacitat de resposta m\u00e8dica a agents qu\u00edmics de guerra desenvolupant ant\u00eddots efectius que aconsegueixin protegir tant al personal militar com a la poblaci\u00f3 civil. “La defensa moderna ha de contemplar un enfocament integral que combini tecnologia, estrat\u00e8gia i ci\u00e8ncia. En un escenari global cada vegada m\u00e9s desafiador, apostar per la innovaci\u00f3 al sector de la defensa no \u00e9s una opci\u00f3, sin\u00f3 una necessitat. A aix\u00f2 se suma que la inversi\u00f3 en tecnologies disruptives i aplicacions m\u00e8diques tamb\u00e9 impulsa la competitivitat industrial i cient\u00edfica del pa\u00eds”, conclouen.<\/p>\n

Reconegut divulgador de la hist\u00f2ria contempor\u00e0nia, la literatura espanyola dels Segles d’Or i la medicina i farmacologia, L\u00f3pez Mu\u00f1oz \u00e9s doctor en Medicina i Cirurgia i doctor en Llengua i Literatura Espanyoles, especialista en Medicina Farmac\u00e8utica i diplomat en Estudis sobre l’Holocaust per l’Escola Internacional per als Estudis de l’Holocaust<\/strong> de Iad Vaixem, a Jerusalem. \u00c9s investigador de l’Institut de Recerca Hospital 12 d’Octubre<\/strong> de Madrid i membre de prestigioses acad\u00e8mies cient\u00edfiques internacionals. Ha participat en nombroses recerques i \u00e9s autor de monografies i articles en les seves \u00e0rees d’investigaci\u00f3. Recentment ha estat nomenat de forma honor\u00edfica coronel de Kentucky mitjan\u00e7ant carta patent atorgada el 29 de juliol del 2024 pel governador de l’Estat de Kentucky, Andy Beshear<\/strong>, i reconegut com a Gu\u00e0rdia Civil Honorari<\/strong>, la m\u00e0xima distinci\u00f3 civil del cos i que atorga de forma excepcional. Ja era professor honor\u00edfic de la Gu\u00e0rdia Civil<\/strong>.<\/p>\n

Llegiu l’article<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"

Francisco L\u00f3pez Mu\u00f1oz aborda les caracter\u00edstiques menys conegudes d’un producte d’\u00fas habitual que a Europa no arriba a considerar-se un medicament, a l’article “La melatonina y la guerra qu\u00edmica: por qu\u00e9 la inversi\u00f3n en defensa tambi\u00e9n debe cubrir la protecci\u00f3n m\u00e9dica”<\/p>\n","protected":false},"author":12,"featured_media":123421,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[332,455,442,380,213],"tags":[],"class_list":["post-161560","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biologia-ca","category-ciencies-de-la-salut","category-ciencies-farmaceutiques-ciencies-de-la-salut","category-conflictes-bellics","category-medicina-i-cirurgia","et-has-post-format-content","et_post_format-et-post-format-standard"],"yoast_head":"\nLa melatonina i la guerra qu\u00edmica - 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