{"id":112385,"date":"2022-02-03T12:29:57","date_gmt":"2022-02-03T12:29:57","guid":{"rendered":"https:\/\/raed.academy\/?p=112385"},"modified":"2022-02-04T18:57:52","modified_gmt":"2022-02-04T18:57:52","slug":"el-paxlovid-arriba-a-europa-reconegut-com-el-primer-farmac-efectiu-en-la-llluita-contra-la-covid","status":"publish","type":"post","link":"https:\/\/raed.academy\/ca\/el-paxlovid-arriba-a-europa-reconegut-com-el-primer-farmac-efectiu-en-la-llluita-contra-la-covid\/","title":{"rendered":"El Paxlovid arriba a Europa reconegut com el primer f\u00e0rmac efectiu en la lluita contra la Covid"},"content":{"rendered":"

Francisco L\u00f3pez Mu\u00f1oz<\/em><\/strong><\/a>
\nProfessor de Farmacologia, vicerector de Recerca i Ci\u00e8ncia i director de l’Escola Internacional de Doctorat de la Universitat Camilo Jos\u00e9 Cela i acad\u00e8mic de n\u00famero de la Reial Acad\u00e8mia Europea de Doctors-Barcelona 1914 (RAED).<\/em><\/p>\n

Article publicat al portal especialitzat The Conversation el 27 de gener del 2022<\/em><\/p>\n

\"Francisco

Dr. Francisco L\u00f3pez Mu\u00f1oz<\/p><\/div>\n

Francisco L\u00f3pez Mu\u00f1oz<\/em><\/strong><\/a>, professor de Farmacologia de la Universitat Camilo Jos\u00e9 Cela<\/strong> i acad\u00e8mic de n\u00famero de la Reial Acad\u00e8mia Europea de Doctors-Barcelona 1914<\/strong> (RAED), incideix en les caracter\u00edstiques i estat legal de l’\u00faltim f\u00e0rmac que ha aparegut contra la Covid-19 a l’article “Paxlovid: la Agencia Europea de Medicamentos autoriza el nuevo f\u00e1rmaco antiviral contra la Covid-19”<\/strong>, una revisi\u00f3 i ampliaci\u00f3 de “Paxlovid: el nuevo tratamiento antiviral oral contra la Covid-19 ya est\u00e1 autorizado”<\/strong>. Tots dos han estat publicats al portal especialitzat The Conversation<\/strong> els passats 4 i 27 de gener i reprodu\u00efts per nombrosos mitjans de comunicaci\u00f3 espanyols i hispanoamericans. L’acad\u00e8mic signa els articles juntament amb Jos\u00e9 Antonio Guerra Guirao<\/strong>, professor de Farmacologia i Toxicologia de la Facultat de Farm\u00e0cia de la Universitat Complutense de Madrid<\/strong>.<\/p>\n

Aquesta revisi\u00f3 parteix de l’aprovaci\u00f3 d’aquest nou f\u00e0rmac el 24 de gener passat per part de l’Ag\u00e8ncia Europea del Medicament<\/strong>, que ja ho havia autoritzat en un context d’emerg\u00e8ncia, un cop l’Administraci\u00f3 d’Aliments i Medicaments dels Estats Units<\/strong> (FDA) ho fes el 22 de desembre, un mes abans, i comenc\u00e9s el seu \u00fas sistem\u00e0tic amb pacients greus. Aix\u00ed mateix, l’Ag\u00e8ncia Reguladora de Salut i Medicines<\/strong> del Regne Unit tamb\u00e9 va autoritzar el 31 de desembre l’\u00fas d’un medicament que va considerar “segur i efectiu” per reduir les possibilitats d’hospitalitzaci\u00f3 i de mort en pacients adults d’alt risc.<\/p>\n

“L’FDA va emetre una Autoritzaci\u00f3 d’\u00das d’Emerg\u00e8ncia per a l’\u00fas de Paxlovid<\/strong> en el tractament de la Covid-19 d’intensitat lleu a moderada, en subjectes adults i pacients pedi\u00e0trics (de 12 anys o m\u00e9s grans que pesin almenys 40 quilograms), que donin positiu a les proves de SARS-CoV-2 i que presentin un alt risc d’emmalaltir greument, incloent-hi l’hospitalitzaci\u00f3 o la mort”, expliquen els autors posant en context l’\u00fas d’aquest f\u00e0rmac.<\/p>\n

\"Paxlovid\"L\u00f3pez Mu\u00f1oz<\/strong> i Guerra Guirao<\/strong> detallen que es tracta d’un preparat a base de dos antivirals: un de nou desenvolupament, el Nirmatrelvir<\/strong>, i un altre de cl\u00e0ssic, \u00e0mpliament utilitzat en altres infeccions virals, el Ritonavir<\/strong>, empacats conjuntament per a la seva utilitzaci\u00f3 oral. El f\u00e0rmac nom\u00e9s es dispensar\u00e0 sota prescripci\u00f3 m\u00e8dica i s’ha de prendre com m\u00e9s aviat millor despr\u00e9s del diagn\u00f2stic de la Covid-19, dins dels cinc dies seg\u00fcents a l’aparici\u00f3 dels s\u00edmptomes. Ara com ara, el Paxlovid no est\u00e0 autoritzat per a la prevenci\u00f3 de la malaltia o per al tractament posterior a l’exposici\u00f3 al SARS-CoV-2, ni tampoc per a l’inici del tractament en persones que requereixen hospitalitzaci\u00f3 a causa d’un quadre greu. L\u00f2gicament, no constitueix una alternativa a la vacunaci\u00f3.<\/p>\n

“En un moment de gran transcend\u00e8ncia en el control de la pand\u00e8mia per l’augment de la incid\u00e8ncia de casos a escala mundial, l’aparici\u00f3 de noves variants del virus, i fins i tot infeccions en pacients amb pauta de vacunaci\u00f3 completa i refor\u00e7ada, la disponibilitat d’un segon agent antiviral per via oral espec\u00edfic per a aquesta infecci\u00f3, despr\u00e9s de la recent autoritzaci\u00f3 del Molnupiravir<\/strong>, suposa un aven\u00e7 rellevant en la lluita contra la Covid-19. A m\u00e9s, la companyia Pfizer<\/strong> s’ha comprom\u00e8s a fer m\u00e9s accessible aquest tractament antiviral als pacients que la necessitin, mitjan\u00e7ant una pol\u00edtica de preus escalonada basada en el nivell d’ingressos mitjans de cada pa\u00eds, a fi de promoure l’equitat d’acc\u00e9s a tot el m\u00f3n”, conclouen tots dos experts.<\/p>\n

Llegiu l’article<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"

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