{"id":104043,"date":"2021-06-25T17:09:38","date_gmt":"2021-06-25T17:09:38","guid":{"rendered":"https:\/\/raed.academy\/?p=104043"},"modified":"2021-06-26T14:38:46","modified_gmt":"2021-06-26T14:38:46","slug":"un-segle-dinsulina-que-va-revolucionar-la-medicina","status":"publish","type":"post","link":"https:\/\/raed.academy\/ca\/un-segle-dinsulina-que-va-revolucionar-la-medicina\/","title":{"rendered":"Un segle d’insulina que va revolucionar la medicina"},"content":{"rendered":"

Francisco L\u00f3pez Mu\u00f1oz<\/em><\/strong><\/a>
\nProfessor de Farmacologia i vice-rector de Recerca i Ci\u00e8ncia i director de l’Escola Internacional de Doctorat de la Universitat Camilo Jos\u00e9 Cela. Acad\u00e8mic de n\u00famero de la Reial Acad\u00e8mia Europea de Doctors-Barcelona 1914 (RAED)<\/em><\/p>\n

Article publicat al portal especialitzat The Conversation i al diari “El Imparcial” de M\u00e8xic el 2 de maig del 2021<\/em><\/p>\n

\"Dr.

Dr. Francisco L\u00f3pez Mu\u00f1oz<\/p><\/div>\n

Francisco L\u00f3pez Mu\u00f1oz<\/em><\/strong><\/a>, professor de Farmacologia de la Universitat Camilo Jos\u00e9 Cela<\/strong> i acad\u00e8mic de n\u00famero de la Reial Acad\u00e8mia Europea de Doctors-Barcelona 1914<\/strong> (RAED), explica el gran aven\u00e7 m\u00e8dic que va suposar el descobriment de la insulina i els tractaments amb ella de la diabetis a l’article “Un siglo de insulina: cuando la diabetes dej\u00f3 de ser necesariamente mortal”<\/strong>, publicat al portal especialitzat The Conversation<\/strong> i al diari “El Imparcial”<\/strong> de M\u00e8xic el passat 2 de maig. L’acad\u00e8mic signa aquest article al costat de Cecilio \u00c1lamo<\/strong>, catedr\u00e0tic de Farmacologia de la Universitat d’Alcal\u00e1 d’Henares<\/strong>.<\/p>\n

Tots dos especialistes assenyalen com a l’actualitat 400 milions de persones pateixen diabetis mellitus i que el 8% de la poblaci\u00f3 occidental la desenvolupar\u00e0 al llarg de la seva vida. “Tot i que avui \u00e9s un trastorn molt ben conegut i controlat, fa un segle el seu pron\u00f2stic era dram\u00e0tic i comportava un desenlla\u00e7 fatal despr\u00e9s dels primers mesos de la diagnosi en nens i adults joves. Tot va canviar el 1921, quan va tenir lloc un dels m\u00e9s importants aven\u00e7os de la hist\u00f2ria de la medicina: el descobriment de la insulina. Aquest era l’origen, i al seu torn la soluci\u00f3, de la grav\u00edssima patologia”, inicien els dos experts el seu article.<\/p>\n

\"\"L\u00f3pez Mu\u00f1oz<\/strong> i \u00c1lamo<\/strong> apunten diversos dels precedents cient\u00edfics de la descoberta, aturant-se, entre d’altres, als investigadors alemanys Joseph von Mering<\/strong> i Oskar Minkovsky<\/strong>, que el 1889 van confirmar que la resecci\u00f3 del p\u00e0ncrees al gos indu\u00efa un quadre sever de diabetis. Aix\u00f2 els va fer pensar en l’exist\u00e8ncia d’alguna subst\u00e0ncia pancre\u00e0tica necess\u00e0ria per a la regulaci\u00f3 dels nivells de glucosa de l’organisme. El 1909, Jean de Meyer<\/strong> va encunyar el po\u00e8tic nom d’insulina (d’\u00ednsula, illa) per designar la subst\u00e0ncia, encara no identificada, produ\u00efda en el que el tamb\u00e9 alemany Paul Langerhans<\/strong> havia denominat illots, una s\u00e8rie de grups de c\u00e8l\u00b7lules ben diferenciats al p\u00e0ncrees, que eren capa\u00e7os de reduir la glucosa a la sang.<\/p>\n

“Al gener del 1922, un pacient diab\u00e8tic de 14 anys d’edat, anomenat Leonard Thompson<\/strong>, que pesava 29 quilos a causa de la seva malaltia, va ser el primer en rebre l’extracte pancre\u00e0tic obtingut per Frederick Grant Banting<\/strong> i Charles Best<\/strong>. El tractament no va tenir \u00e8xit ia causa d’una reacci\u00f3 al\u00b7l\u00e8rgica severa i es van veure obligats a suspendre’l. No obstant aix\u00f2, nom\u00e9s 12 dies despr\u00e9s es va reiniciar el tractament amb l’administraci\u00f3 del preparat elaborat per James Collip<\/strong>, que havia seguit un conscienci\u00f3s proc\u00e9s d’eliminaci\u00f3 de molts dels contaminants que encara romanien a l’extracte de Banting i Best. Aquest \u00faltim preparat va funcionar considerablement b\u00e9, va reduir els nivells de glucosa en sang i orina, els cossos cet\u00f2nics i gran part de la simptomatologia diab\u00e8tica”, expliquen els investigadors.<\/p>\n

 <\/p>\n

Llegiu l’article a The Conversation<\/a><\/h2>\n

Llegiu l’article a “El Imparcial”<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"

Francisco L\u00f3pez Mu\u00f1oz explica el gran aven\u00e7 m\u00e8dic de la descoberta de la insulina i els tractaments amb ella de la diabetis en l’article “Un siglo de insulina: cuando la diabetes dej\u00f3 de ser necesariamente mortal”<\/p>\n","protected":false},"author":12,"featured_media":104028,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[213],"tags":[],"class_list":["post-104043","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina-i-cirurgia","et-has-post-format-content","et_post_format-et-post-format-standard"],"yoast_head":"\nUn segle d'insulina que va revolucionar la medicina - Reial Acad\u00e8mia Europea de Doctors<\/title>\n<meta name=\"description\" content=\"Francisco L\u00f3pez Mu\u00f1oz explica el gran aven\u00e7 m\u00e8dic de la descoberta de la insulina i els tractaments amb ella de la diabetis\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/raed.academy\/ca\/un-segle-dinsulina-que-va-revolucionar-la-medicina\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un segle d'insulina que va revolucionar la medicina - 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